当前位置: X-MOL 学术J. Am. Acad. Dermatol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus
Journal of the American Academy of Dermatology ( IF 13.8 ) Pub Date : 2019-02-05 , DOI: 10.1016/j.jaad.2019.01.072
Dimitrios Rigopoulos , Robert Baran , Soumiya Chiheb , Carlton Ralph Daniel , Nilton Di Chiacchio , Stamatis Gregoriou , Chander Grover , Eckart Haneke , Matilde Iorizzo , Marcel Pasch , Bianca Maria Piraccini , Phoebe Rich , Bertrand Richert , Natalia Rompoti , Adam I. Rubin , Archana Singal , Michela Starace , Antonella Tosti , Ioanna Triantafyllopoulou , Martin Zaiac

Nail involvement in psoriasis is common, and the severity of it does not always parallel the intensity of cutaneous disease. We created a consensus group, of which the aim was to provide practical recommendations for the treatment of nail psoriasis in patients without skin psoriasis or with mild skin lesions with no indication for a systemic treatment. This collaborative process was conducted by an international panel of dermatologists with special expertise in nail disorders, using formal consensus methods. During this process, the panel strived to establish an agreement regarding the definition of nail psoriasis, the severity of nail psoriasis, and treatment response. Treatment recommendations are provided regarding nail psoriasis severity and matrix or bed involvement. Few-nail disease was considered as nail psoriasis affecting ≤3 nails. In the case of matrix involvement only, intralesional steroid injections were considered the treatment of choice. Topical steroids alone or in combination with topical vitamin D analogues were suggested for nail psoriasis limited to the nail bed. For the systemic treatment of nail psoriasis acitretin, methotrexate, cyclosporine, small molecules, and biologics may be employed.



中文翻译:

成年无或轻度皮肤牛皮癣患者的指甲牛皮癣的定义,评估和治疗的建议:皮肤科医生和指甲专家小组的共识

指甲累及牛皮癣是很常见的,其严重程度并不总是与皮肤疾病的强度相提并论。我们创建了一个共识小组,其目的是为没有皮肤银屑病或轻度皮肤损伤且无全身治疗指征的指甲银屑病患者提供实用的建议。这个合作过程是由国际皮肤病专家小组在指甲疾病方面具有专门知识的,采用正式的共识方法进行的。在此过程中,专家小组努力就指甲牛皮癣的定义,指甲牛皮癣的严重程度和治疗反应达成共识。提供有关指甲牛皮癣严重程度和基质或床受累的治疗建议。很少有指甲疾病被认为是影响≤3只指甲的牛皮癣。仅在基质受累的情况下,病灶内类固醇注射被认为是治疗的选择。建议将局部类固醇单独使用或与局部维生素D类似物组合用于仅限于指甲床的指甲牛皮癣。对于甲型牛皮癣的全身治疗,阿维A,甲氨蝶呤,环孢素,小分子和生物制剂都可以使用。

更新日期:2019-07-07
down
wechat
bug