Women are employed in increasing numbers as gasoline station attendants, a work category with risk of exposure to benzene. We have assessed the effect of gender on biomarkers of occupational benzene exposure. Gasoline station attendants (20 men and 20 women) and 40 control individuals (20 men and 20 women) with no history of occupational benzene exposure were evaluated. Benzene exposure was monitoring by environmental and biological measurements. Urinary trans,trans-muconic acid levels, well-known genetic and hematological alterations linked to benzene exposure, and non-cancer effects on the immune, hepatic, and renal systems were investigated. Our results suggest a potential effect of gender on some effects of occupational benzene exposure, particularly the hematological parameters and trans,trans-muconic acid levels. Despite limitations of our study, our findings provide important considerations about occupational exposure of women to benzene and may contribute to the development of occupational protection standards.

中文翻译：

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接触苯的加油站服务员的生物监测：性别的影响。

越来越多的女性被聘为加油站服务员，这是一个有接触苯的风险的工作类别。我们评估了性别对职业苯暴露生物标志物的影响。对没有职业苯暴露史的加油站服务员（20 名男性和 20 名女性）和 40 名对照个体（20 名男性和 20 名女性）进行了评估。苯暴露通过环境和生物测量进行监测。研究了尿液反式、反式粘康酸水平、与苯暴露相关的众所周知的遗传和血液学改变，以及对免疫、肝脏和肾脏系统的非癌症影响。我们的研究结果表明，性别对职业性苯暴露的某些影响具有潜在影响，尤其是血液学参数和反式、反式粘康酸水平。