Abstract In this study, the microstructural, mechanical and biological characterizations of the Ti-25Ta (wt.%) alloy were investigated by means of optical microscope, X-ray diffraction, electron microscope, microhardness test, contact angle goniometer and in vitro cytotoxicity assay. As the alloy underwent heat-treatment at temperatures between 700 °C and 1000 °C for 30 min, its microstructure was a mixture of β phase and needle-like α′′ martensite phase. The analytical results indicated that the volume fraction of the needle-like α′′ martensite phase decreased with increasing heat-treatment temperature. The β transus temperature of the investigated Ti-25Ta alloy was below 700 °C. Moreover, the alloy heat-treated at 900 °C exhibited the maximum hardness Hv 743 ± 12.93. For wettability evaluation, all investigated samples possessed surface hydrophilicity. The cytotoxicity assay results also demonstrated that the heat-treated Ti-25Ta samples have well cell proliferation and adhesion behaviors. Therefore, these results and features could be used to further understand the relationship between the high temperature microstructure, mechanical behavior and in vivo biocompatibility of the Ti-25Ta alloy, and develop as a potential biomedical alloy.

中文翻译：

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用于生物医学应用的有前途的钛钽合金的显微结构、机械和生物特性

摘要 本研究通过光学显微镜、X 射线衍射、电子显微镜、显微硬度试验、接触角测角仪和体外细胞毒性试验研究了 Ti-25Ta (wt.%) 合金的显微组织、力学和生物学特性。 . 由于合金在 700°C 和 1000°C 之间的温度下热处理 30 分钟，其显微组织是 β 相和针状 α'' 马氏体相的混合物。分析结果表明，针状α''马氏体相的体积分数随着热处理温度的升高而降低。所研究的 Ti-25Ta 合金的 β 转变温度低于 700 °C。此外，在 900 °C 下热处理的合金表现出最大硬度 Hv 743 ± 12.93。对于润湿性评估，所有研究的样品都具有表面亲水性。细胞毒性测定结果还表明，热处理后的 Ti-25Ta 样品具有良好的细胞增殖和粘附行为。因此，这些结果和特征可用于进一步了解 Ti-25Ta 合金的高温微观结构、力学行为和体内生物相容性之间的关系，并发展成为一种潜在的生物医学合金。