Background

The relationship between gut microbiota and human health has gradually been recognized. Increasing studies show that the disorder of gut microbiota is related to the occurrence and development of many diseases. Metabolites produced by the gut microbiota are responsible for their extensive regulatory roles. In addition, naturally derived medicine food homology species with low toxicity and high efficiency have been clearly defined owing to their outstanding physiological and pharmacological properties in disease prevention and treatment.

Aim of review

Based on supporting evidence, the current review summarizes the representative work of medicine food homology species targeting the gut microbiota to regulate host pathophysiology and discusses the challenges and prospects in this field. It aims to facilitate the understanding of the relationship among medicine food homology species, gut microbiota, and human health and further stimulate the advancement of more relevant research.

Key scientific concepts of review

As this review reveals, from the initial practical application to more mechanism studies, the relationship among medicine food homology species, gut microbiota, and human health has evolved into an irrefutable interaction. On the one hand, through affecting the population structure, metabolism, and function of gut microbiota, medicine food homology species maintain the homeostasis of the intestinal microenvironment and human health by affecting the population structure, metabolism, and function of gut microbiota. On the other hand, the gut microbiota is also involved in the bioconversion of the active ingredients from medicine food homology species and thus influences their physiological and pharmacological properties.

中文翻译：

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肠道菌群：药食同源物种调控的神奇多功能靶点

背景

肠道菌群与人类健康的关系逐渐被人们认识。越来越多的研究表明，肠道菌群失调与多种疾病的发生、发展有关。肠道微生物群产生的代谢物具有广泛的调节作用。此外，天然来源的低毒、高效的药食同源物种，因其在疾病预防和治疗方面突出的生理药理特性而得到了明确的定义。

审查目的

基于支持证据，本综述总结了针对肠道菌群调节宿主病理生理学的药食同源物种的代表性工作，并讨论了该领域的挑战和前景。旨在促进对药食同源物种、肠道微生物群和人类健康之间关系的理解，并进一步推动更多相关研究的进展。

审查的关键科学概念

正如这篇综述所揭示的那样，从最初的实际应用到更多的机制研究，药食同源物种、肠道菌群和人类健康之间的关系已经演变成无可辩驳的相互作用。一方面，药食同源物种通过影响肠道菌群的种群结构、代谢和功能，通过影响肠道菌群的种群结构、代谢和功能来维持肠道微环境的稳态和人体健康。另一方面，肠道菌群也参与药食同源物种活性成分的生物转化，从而影响其生理和药理特性。