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Cascade Nucleophilic Addition–Cyclic Michael Addition of Arynes and Indoles Bearing Michael Acceptor: A Strategy to Construct Pyrroloacridines and Study of Their Physicochemical Properties
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2023-06-01 , DOI: 10.1021/acs.joc.3c00462
Gurupada Hazra 1 , Sayantan Kundu 1 , Rambabu Dandela 2 , Barla Thirupathi 1
Affiliation  

A facile synthetic approach to 6H-pyrrolo[3,2,1-de]acridines has been developed by using cascade N-nucleophilic addition–cyclic Michael addition process of arynes and indoles substituted with Michael acceptors under metal-free conditions. Additionally, photophysical studies of a few of the newly synthesized pyrroloacridine compounds indicated good fluorescence emission properties.

中文翻译:

级联亲核加成——带有迈克尔受体的芳炔和吲哚的环状迈克尔加成:构建吡咯吖啶的策略及其理化性质的研究

通过在无金属条件下用迈克尔受体取代的芳炔和吲哚的级联N-亲核加成-环状迈克尔加成过程,开发了一种简便的合成6 H-吡咯并[3,2,1- de ]吖啶的方法。此外,一些新合成的吡咯吖啶化合物的光物理研究表明具有良好的荧光发射性能。
更新日期:2023-06-01
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