Co-catalyzed stereospecific C–N and C–O bond formation of oxiranes with diaziridines has been accomplished to furnish tetrahydro-[1,3,4]-oxadiazines at room temperature. Optically active oxiranes can be coupled with high optical purities (>96% ee). Stereoselectivity, functional group tolerance, mechanistic studies using DFT, and natural product modification are the important practical features.

中文翻译：

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钴催化环氧乙烷与二氮丙啶形成立体特异性 C-N/C-O 键

已经完成了环氧乙烷与二氮丙啶的共催化立体特异性 C-N 和 C-O 键形成，以在室温下提供四氢-[1,3,4]-恶二嗪。光学活性环氧乙烷可以与高光学纯度（> 96% ee）偶联。立体选择性、官能团耐受性、使用 DFT 进行机理研究以及天然产物修饰是重要的实用特征。