In Southeast Asia, the natural rubber (Hevea brasiliensis) industry has expanded dramatically, and throughout the production process, a sizeable portion of industrial rubber serum is treated as effluent. L-quebrachitol has been proved as a natural product abundantly present in natural rubber serum. In order to improve the utilization rate of natural rubber, a method was provided to extract L-quebrachitol from industrial rubber serum, and the yield was 0.1∼0.2%. By using mass spectrometer, Fourier transform infrared, and nuclear magnetic resonance spectroscopy, the isolated molecule was identified as L-quebrachitol. Meanwhile, there is a lack of complete research on the antioxidant capacity of L-quebrachitol, and the effect of L-quebrachitol on bone mineral density remains at the cellular level. In this work, L-quebrachitol was confirmed to have a great ability to scavenge free radicals, especially at a concentration of 0.5 mg/mL. The protective capacity of antioxidant enzymes (catalase, total glutathione peroxidase, and superoxide dismutase) and the ability to inhibit lipid peroxidation of L-quebrachitol at concentrations of 50 and 100 μg/mL was remarkable. Furthermore, animal experiment showed that L-quebrachitol at 125 mg/kg·bw can significantly reduce weight gain, increase bone mineral density and bone calcium content of ovariectomized rats. Consequently, L-quebrachitol could be used as a novel antioxidant to prevent oxidative stress-related diseases or as an agent to increase bone density to prevent osteoporosis.

在东南亚，天然橡胶 ( Hevea brasiliensis ) 产业急剧扩张，在整个生产过程中，有相当一部分工业橡胶浆液被作为废水处理。L-白桦糖醇已被证明是天然产物，大量存在于天然橡胶浆液中。为提高天然橡胶的利用率，提出了一种从工业橡胶浆液中提取L-白桦醇的方法，得率为0.1～0.2%。通过质谱、傅里叶变换红外和核磁共振光谱，分离出的分子被鉴定为L-白桦醇。同时，对L的抗氧化能力缺乏完整的研究。-quebrachitol，而L -quebrachitol 对骨矿物质密度的影响保持在细胞水平。在这项工作中，L-白桦糖醇被证实具有强大的清除自由基的能力，尤其是在 0.5 mg/mL 的浓度下。抗氧化酶（过氧化氢酶、总谷胱甘肽过氧化物酶和超氧化物歧化酶）的保护能力和抑制浓度为 50 和 100 μg/mL 的L-白杨木醇脂质过氧化的能力非常显着。此外，动物实验表明， 125 mg/kg·bw的L-白木醇能显着降低去卵巢大鼠的体重增加，增加骨密度和骨钙含量。因此，大号-quebrachitol 可用作新型抗氧化剂以预防氧化应激相关疾病或作为增加骨密度以预防骨质疏松症的药物。