In this experiment, using MXene quantum dot (MQD) as the core and thiamethoxam (TMX) as the template, a dual-functional surface molecularly imprinted polymer nanoprobe (MQD@MIP) for detecting of TMX was synthesized by microwave digestion procedure. And MQD@MIP was characterized in detail. It was found that this nanoprobe had dual function, which not only could specifically recognize TMX, but also could strongly catalyze the new indicator reaction of HAuCl₄-maleic acid to produce gold nanoparticles (AuNPs). The AuNPs exhibit strong surface enhanced Raman scattering (SERS), resonance Rayleigh scattering (RRS) and surface plasmon resonance absorption (Abs) effect. Based on this, a new SERS/RRS/Abs trimode biosensoring platform was constructed for the determination of TMX, with a linear range of 1.0–150, 1.0–150, and 5.0–125 nmol/L TMX, and detection limit of 0.57 nmo/L, 0.84 nmol/L and 3.5 nmol/L, respectively. As a comparison, we used carbon dots (CDs) as the core to prepare surface molecularly imprinted polymers (CD@MIP) nanoprobe, and investigated the catalytic effect on the nanogold indicator reaction and the specific recognition effect on TMX.

本实验以MXene量子点（MQD）为核心，以噻虫嗪（TMX）为模板，采用微波消解法合成了一种用于检测TMX的双功能表面分子印迹聚合物纳米探针（MQD@MIP）。并对 MQD@MIP 进行了详细表征。发现该纳米探针具有双重功能，既能特异性识别TMX，又能强烈催化HAuCl _{4的新指示剂反应}- 马来酸生产金纳米粒子 (AuNPs)。AuNPs 表现出强烈的表面增强拉曼散射 (SERS)、共振瑞利散射 (RRS) 和表面等离子体共振吸收 (Abs) 效应。在此基础上，构建了一个新的SERS/RRS/Abs三模生物传感平台用于TMX的测定，线性范围为1.0-150、1.0-150和5.0-125 nmol/L TMX，检测限为0.57 nmo /L，分别为 0.84 nmol/L 和 3.5 nmol/L。作为对比，我们以碳点（CDs）为核心制备了表面分子印迹聚合物（CD@MIP）纳米探针，考察了其对纳米金指示剂反应的催化作用和对TMX的特异性识别效果。