Meta-analysis of genome-wide association studies of spontaneous coronary artery dissection (SCAD), an important cause of myocardial infarction, identified 11 risk loci that involve genes related to artery integrity and tissue-mediated coagulation. Evidence supports SCAD as a genetically distinct condition from atherosclerotic coronary artery disease.

中文翻译：

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自发性冠状动脉夹层的遗传学和生物学见解

自发性冠状动脉夹层（SCAD）是心肌梗死的一个重要原因，对全基因组关联研究的荟萃分析确定了 11 个涉及动脉完整性和组织介导凝血相关基因的风险位点。有证据支持 SCAD 是一种与动脉粥样硬化性冠状动脉疾病在遗传上不同的疾病。