Atomically precise metal nanoclusters have received tremendous attention due to their unique structures and properties. Although synthetic approaches to this kind of nanomaterial have been well developed, methods toward precision functionalization of the as-synthesized metal nanoclusters are extremely limited, hindering their interfacial modification and related performance improvement. Herein, an amidation strategy has been developed for the precision functionalization of the Au₁₁ nanocluster based on preorganized nitrogen sites. The nanocluster amidation did not change the number of gold atoms in the Au₁₁ kernel and their bonding mode to the surface ligands but slightly modified the arrangement of gold atoms with the introduction of functionality and chirality, thus representing a relatively mild method for the modification of metal nanoclusters. The stability and oxidation barrier of the Au₁₁ nanocluster are also improved accordingly. The method developed here would be a generalizable strategy for the precision functionalization of metal nanoclusters.

中文翻译：

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用于 Au11 酰胺化的预组织氮位点：金属纳米团簇精确功能化的通用策略

原子精确的金属纳米团簇由于其独特的结构和性质而受到了极大的关注。尽管这种纳米材料的合成方法已经得到很好的发展，但对合成后的金属纳米团簇进行精确功能化的方法极为有限，阻碍了它们的界面修饰和相关性能的提高。在此，已经开发了一种酰胺化策略，用于基于预组织氮位点的Au ₁₁纳米团簇的精确功能化。_{纳米团簇酰胺化并没有改变 Au 11}中金原子的数量内核及其与表面配体的键合模式，但通过引入功能性和手性略微改变了金原子的排列，因此代表了一种相对温和的金属纳米团簇修饰方法。_{Au 11}纳米团簇的稳定性和抗氧化性也相应提高。这里开发的方法将成为金属纳米团簇精确功能化的通用策略。