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Visible-Light-Promoted Desulfurization to Synthesize Deoxyglycosides
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2023-05-25 , DOI: 10.1021/acs.joc.3c00046
Tao Luo 1 , Yang-Fan Guo 1 , Tian-Tian Xu 1 , Hai Dong 1, 2
Affiliation  

In this study, we have successfully applied a visible-light-promoted desulfurization method to the synthesis of deoxysugars, especially 1-deoxyglycose, 2,4-deoxyglycosides, and 2-deoxyglycosides with exclusive α-configuration. Compared to the reported desulfurization under UV light (500 W mercury lamp), this desulfurization under visible light (20 W blue LED) is easy to operate since it does not require a dedicated photochemical reactor, occurs under very mild conditions, and is able to avoid many of the side reactions that often occur during the UV-induced desulfurization.

中文翻译:

可见光促进脱硫合成脱氧糖苷

在本研究中,我们成功地将可见光促进的脱硫方法应用于脱氧糖的合成,特别是具有独特α构型的1-脱氧糖、2,4-脱氧糖苷和2-脱氧糖苷。与报道的紫外光脱硫(500 W汞灯)相比,这种可见光脱硫(20 W蓝色LED)易于操作,因为它不需要专用的光化学反应器,在非常温和的条件下发生,并且能够避免了紫外线脱硫过程中经常发生的许多副反应。
更新日期:2023-05-25
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