A mild, efficient, and transition-metal-free three-component coupling reaction involving arynes, phosphites, and aldehydes was established to afford 3-mono-substituted benzoxaphosphole 1-oxides. A range of 3-mono-substituted benzoxaphosphole 1-oxides was obtained from both aryl- and aliphatic-substituted aldehydes in moderate to good yields. Moreover, the synthetic utility of the reaction was demonstrated by a Gram-scale reaction and the transformation of the products into various P-containing bicycles.

中文翻译：

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涉及芳烃、亚磷酸酯和醛的 3-单取代苯并氧磷 1-氧化物的三组分偶联反应

建立了一种涉及芳烃、亚磷酸酯和醛的温和、高效且不含过渡金属的三组分偶联反应，以得到 3-单取代的苯并氧磷杂环磷酯 1-氧化物。从芳基和脂肪族取代的醛中以中等至良好的产率获得了一系列 3-单取代的苯并氧磷杂环磷酯 1-氧化物。此外，通过克级反应和将产物转化为各种含磷自行车，证明了该反应的合成效用。