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Electrochemical Radical Reactions of Enol Acetates and Free Alcohols Directly Access to α-Alkoxylated Carbonyl Compounds
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2023-05-24 , DOI: 10.1021/acs.joc.3c00635
Fan Wu 1 , Yu Guo 1 , Zihao Ren 1 , Zixuan Chen 1 , Xiaoqin Liu 1 , Chang Wang 2 , Liangce Rong 1
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The efficient intermolecular alkoxylation reactions of various enol acetates and different alcohols are developed in the electrochemical process for the first time. Enol acetates derived from either aromatic, alkyl, or alicyclic ketones, and abundant free alcohols directly used in this synthetic strategy, make this transformation very valuable in synthesis and application in the future.

中文翻译:

烯醇乙酸酯和游离醇的电化学自由基反应直接生成α-烷氧基化羰基化合物

首次在电化学过程中开发了各种烯醇乙酸酯和不同醇的高效分子间烷氧基化反应。衍生自芳香族、烷基或脂环族酮的烯醇乙酸酯,以及直接用于该合成策略的丰富的游离醇,使得这种转化在未来的合成和应用中非常有价值。
更新日期:2023-05-24
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