The aim of the present study was to obtain bioactive compounds from hibiscus leaves through supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE). For SFE, temperature, pressure, and co-solvent were evaluated on extraction yield (X₀), content of bioactive compounds and antioxidant activity (AA). For PLE, temperature and solvent composition were evaluated on the same responses. The highest X₀ was observed at 60 °C, 300 bar and 15% of co-solvent for SFE, and at 100 °C and ethanol 75% for PLE. For bioactive compounds, different results were observed. For SFE, the best condition was at 60 ºC, 100 bar and 15% of co-solvent, and for PLE at 80 ºC with ethanol 99.5%. Regarding AA, SFE extracts presented highest values at 60 ºC, 100 bar and 5% of co-solvent while PLE presented better results at 60 °C and 99.5%. Chlorogenic acid and quercetin were the main compounds identified in the extracts.

本研究的目的是通过超临界流体萃取 (SFE) 和加压液体萃取 (PLE) 从芙蓉叶中提取生物活性化合物。对于 SFE，温度、压力和助溶剂对提取率 ( X ₀ )、生物活性化合物的含量和抗氧化活性 (AA) 进行了评估。对于 PLE，根据相同的响应评估温度和溶剂组成。最高X ₀对于 SFE，在 60 °C、300 bar 和 15% 的助溶剂下观察，对于 PLE 在 100 °C 和 75% 的乙醇下观察。对于生物活性化合物，观察到不同的结果。对于 SFE，最佳条件是 60 ºC、100 bar 和 15% 的助溶剂，而对于 PLE，最佳条件是 80 ºC 和 99.5% 的乙醇。关于 AA，SFE 提取物在 60 ºC、100 bar 和 5% 的助溶剂下表现出最高值，而 PLE 在 60 °C 和 99.5% 下表现出更好的结果。绿原酸和槲皮素是提取物中鉴定出的主要化合物。