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A Systematic Design and Synthesis of PET-based Fluorescent Probes for Monitoring pH During Mitophagy
Chemistry - An Asian Journal ( IF 4.1 ) Pub Date : 2023-05-01 , DOI: 10.1002/asia.202300308
Rashmi Yadav 1 , Subrata Munan 1 , Mudassar Ali 2 , Koyeli Mapa 2 , Animesh Samanta 1
Affiliation  

We systematically synthesized three fluorophores with variable spacers. An efficient PET process was observed for PM-C2 with a two-carbon spacer. The mitochondria-specific probe can monitor mitophagy process by monitoring pH change.

中文翻译:

用于监测线粒体自噬过程中 pH 值的 PET 荧光探针的系统设计和合成

我们系统地合成了三种具有可变间隔基的荧光团。观察到具有双碳间隔基的PM-C2的高效 PET 工艺。线粒体特异性探针可以通过监测pH变化来监测线粒体自噬过程。
更新日期:2023-05-01
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