Various analogs of rhodomyrtone with different acyl groups at C7 were prepared by selective chlorination of the core structure at C5 followed by a Duff formylation at C7. After protection of the phenolic OH groups, a sequence of Grignard reaction, oxidation, and deprotection led to the analogs. Some of them turned out to be very active.

中文翻译：

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C7 修饰的红糖苷类似物的合成

通过在 C5 处选择性氯化核心结构，然后在 C7 处进行 Duff 甲酰化，制备了在 C7 处具有不同酰基的桃金娘酮的各种类似物。在保护酚羟基后，一系列格氏反应、氧化和脱保护得到类似物。事实证明，其中一些人非常活跃。