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Distal memory in wound healing and cancer
Nature Cell Biology ( IF 21.3 ) Pub Date : 2023-04-20 , DOI: 10.1038/s41556-023-01132-w
Frank Lyko 1
Affiliation  

Skin wounds induce an epigenetic memory that accelerates the healing of subsequent injuries. The underlying mechanism is now shown to involve epigenetic chromatin modifications in stem cells from a field of distal hair follicles that surround the injury. Importantly, this mechanism also results in a predisposition for skin cancer development.

中文翻译:

伤口愈合和癌症中的远端记忆

皮肤伤口会诱发表观遗传记忆,加速后续伤口的愈合。现在表明,潜在的机制涉及来自损伤周围远端毛囊区域的干细胞的表观遗传染色质修饰。重要的是,这种机制还会导致皮肤癌的发生。
更新日期:2023-04-21
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