Reconstructing phylogenetic trees from large collections of genome sequences is a computationally challenging task. We developed MAPLE, a method for performing phylogenetic inference on large numbers of closely related genomes, which might be useful when studying the evolution and spread of SARS-CoV-2 and of infectious pathogens in future pandemics.

中文翻译：

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从大流行规模的基因组数据集中推断系统发育

从大量基因组序列中重建系统发育树是一项计算上具有挑战性的任务。我们开发了 MAPLE，这是一种对大量密切相关的基因组进行系统发育推断的方法，在研究 SARS-CoV-2 和传染性病原体在未来大流行中的进化和传播时可能会有用。