当前位置：
X-MOL 学术
›
Clin. Interventions Aging
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Clinical Outcome and Safety of Lumboperitoneal Shunt in the Treatment of Non-Obstructive Hydrocephalus
Clinical Interventions in Aging ( IF 3.6 ) Pub Date : 2023-03-23 , DOI: 10.2147/cia.s401116 Ning-Ping Foo , Yang Chien Tun , Che Chao Chang , Hung-Lin Lin , Cheng-Hsin Cheng , Hao-Yu Chuang
Clinical Interventions in Aging ( IF 3.6 ) Pub Date : 2023-03-23 , DOI: 10.2147/cia.s401116 Ning-Ping Foo , Yang Chien Tun , Che Chao Chang , Hung-Lin Lin , Cheng-Hsin Cheng , Hao-Yu Chuang
Objective: This study aimed to evaluate the functional outcomes of lumboperitoneal (LP) shunt for the treatment of non-obstructive hydrocephalus.
Methods: We retrospectively studied the clinical surgical results of 172 adult patients with hydrocephalus who underwent LP shunt surgery between June 2014 and June 2019. Data regarding the following were collected: pre- and postoperative symptom status, third ventricle width changes, Evans index, and postoperative complications. Additionally, the baseline and follow-up Glasgow Coma Scale (GCS) score, Glasgow Outcome Scale (GOS), and Modified Rankin Scale (mRS) scores were investigated. All patients were followed up for ≥ 12 months using clinical interview and braining imaging using computed tomography (CT) scan or magnetic resonance imaging (MRI).
Results: Majority of patients presented with normal pressure hydrocephalus as the etiology of their disease (48.8%), followed by cardiovascular accident (28.5%), trauma (19.7%), and brain tumor (3%). The mean GCS, GOS, and mRS improved postoperatively. The average period from symptomatic onset to surgery was 402 days. The average width of the third ventricle on CT scan or MRI was 11.43 mm preoperatively and 10.8 mm postoperatively (P< 0.001). The Evans index improved from 0.258 to 0.222 after operation. The symptomatic improvement score was 7.0, with a complication rate of 7%.
Conclusion: Significant improvement was observed in the functional score and brain image after LP shunt placement. Moreover, the satisfaction with symptomatic improvement after surgery remains high. LP shunt operation is a viable alternative in the treatment of non-obstructive hydrocephalus due to the low complication rate, fast recovery, and high satisfaction.
Keywords: clinical outcome, complication, lumboperitoneal shunt, non-obstructive hydrocephalus
中文翻译：
腰腹腔分流术治疗非梗阻性脑积水的临床疗效及安全性
目的：本研究旨在评估腰腹腔（LP）分流术治疗非梗阻性脑积水的功能结果。
方法：我们回顾性研究了 2014 年 6 月至 2019 年 6 月接受 LP 分流手术的 172 例成年脑积水患者的临床手术结果。收集了以下数据：术前和术后症状状态、第三脑室宽度变化、Evans 指数和术后并发症。此外，还研究了基线和后续格拉斯哥昏迷量表 (GCS) 评分、格拉斯哥结果量表 (GOS) 和改良兰金量表 (mRS) 评分。使用临床访谈和使用计算机断层扫描 (CT) 扫描或磁共振成像 (MRI) 的脑成像对所有患者进行了 ≥ 12 个月的随访。
结果：大多数患者的病因是正常压力脑积水 (48.8%)，其次是心血管意外 (28.5%)、外伤 (19.7%) 和脑肿瘤 (3%)。术后平均 GCS、GOS 和 mRS 得到改善。从出现症状到手术的平均时间为 402 天。CT扫描或MRI显示的第三脑室平均宽度术前为11.43 mm，术后为10.8 mm（P<0.001）。手术后Evans指数由0.258改善至0.222。症状改善评分为 7.0，并发症发生率为 7%。
结论：放置 LP 分流器后，功能评分和脑图像均有显着改善。此外，手术后对症状改善的满意度仍然很高。LP分流术具有并发症发生率低、恢复快、满意度高等优点，是治疗非梗阻性脑积水的可行方案。
Keywords:临床结果, 并发症, 腰腹腔分流术, 非梗阻性脑积水
更新日期：2023-03-23
Methods: We retrospectively studied the clinical surgical results of 172 adult patients with hydrocephalus who underwent LP shunt surgery between June 2014 and June 2019. Data regarding the following were collected: pre- and postoperative symptom status, third ventricle width changes, Evans index, and postoperative complications. Additionally, the baseline and follow-up Glasgow Coma Scale (GCS) score, Glasgow Outcome Scale (GOS), and Modified Rankin Scale (mRS) scores were investigated. All patients were followed up for ≥ 12 months using clinical interview and braining imaging using computed tomography (CT) scan or magnetic resonance imaging (MRI).
Results: Majority of patients presented with normal pressure hydrocephalus as the etiology of their disease (48.8%), followed by cardiovascular accident (28.5%), trauma (19.7%), and brain tumor (3%). The mean GCS, GOS, and mRS improved postoperatively. The average period from symptomatic onset to surgery was 402 days. The average width of the third ventricle on CT scan or MRI was 11.43 mm preoperatively and 10.8 mm postoperatively (P< 0.001). The Evans index improved from 0.258 to 0.222 after operation. The symptomatic improvement score was 7.0, with a complication rate of 7%.
Conclusion: Significant improvement was observed in the functional score and brain image after LP shunt placement. Moreover, the satisfaction with symptomatic improvement after surgery remains high. LP shunt operation is a viable alternative in the treatment of non-obstructive hydrocephalus due to the low complication rate, fast recovery, and high satisfaction.
Keywords: clinical outcome, complication, lumboperitoneal shunt, non-obstructive hydrocephalus
中文翻译：
腰腹腔分流术治疗非梗阻性脑积水的临床疗效及安全性
目的：本研究旨在评估腰腹腔（LP）分流术治疗非梗阻性脑积水的功能结果。
方法：我们回顾性研究了 2014 年 6 月至 2019 年 6 月接受 LP 分流手术的 172 例成年脑积水患者的临床手术结果。收集了以下数据：术前和术后症状状态、第三脑室宽度变化、Evans 指数和术后并发症。此外，还研究了基线和后续格拉斯哥昏迷量表 (GCS) 评分、格拉斯哥结果量表 (GOS) 和改良兰金量表 (mRS) 评分。使用临床访谈和使用计算机断层扫描 (CT) 扫描或磁共振成像 (MRI) 的脑成像对所有患者进行了 ≥ 12 个月的随访。
结果：大多数患者的病因是正常压力脑积水 (48.8%)，其次是心血管意外 (28.5%)、外伤 (19.7%) 和脑肿瘤 (3%)。术后平均 GCS、GOS 和 mRS 得到改善。从出现症状到手术的平均时间为 402 天。CT扫描或MRI显示的第三脑室平均宽度术前为11.43 mm，术后为10.8 mm（P<0.001）。手术后Evans指数由0.258改善至0.222。症状改善评分为 7.0，并发症发生率为 7%。
结论：放置 LP 分流器后，功能评分和脑图像均有显着改善。此外，手术后对症状改善的满意度仍然很高。LP分流术具有并发症发生率低、恢复快、满意度高等优点，是治疗非梗阻性脑积水的可行方案。
Keywords:临床结果, 并发症, 腰腹腔分流术, 非梗阻性脑积水
京公网安备 11010802027423号