Phytopathogenic fungi can cause a direct loss in economic value of agriculture. Especially Valsa mali Miyabe et Yamada, a devastating phytopathogenic disease especially threatening global apple production, is very difficult to control and manage. To discover new potential antifungal agents, a series of thiosemicarbazone derivatives of 3-acetyl-N-benzylindoles were prepared. Their antifungal activities were first tested against six typically phytopathogenic fungi including Curvularia lunata, Valsa mali, Alternaria alternate, Fusarium graminearum, Botrytis cinerea and Fusarium solani. Then their mechanism of action against V. mali was investigated.

中文翻译：

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天然产物在作物保护中的应用：3-乙酰基-N-苯甲基吲哚的缩氨基硫脲衍生物作为抗真菌剂及其作用机制

植物病原真菌可造成农业经济价值的直接损失。尤其是苹果腐烂病（ Valsa mali Miyabe et Yamada），这是一种毁灭性的植物病害，尤其威胁全球苹果生产，控制和管理非常困难。为了发现新的潜在抗真菌剂，制备了一系列3-乙酰基-N-苄基吲哚的缩氨基硫脲衍生物。他们的抗真菌活性首先针对六种典型的植物病原真菌进行了测试，包括新月弯孢菌、苹果腐烂病菌、交替链格孢菌、禾谷镰刀菌、灰葡萄孢和茄病镰刀菌。然后他们的行动机制对马里病毒进行了调查。