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A human VEGF magnetic molecularly imprinted polymer for drug-free anti-angiogenesis and photothermal therapy of tumors
Chemical Communications ( IF 4.9 ) Pub Date : 2023-03-14 , DOI: 10.1039/d3cc00088e Mengzhao Wen 1 , Haizhu Shi 1 , Yu Wan 1 , Jiateng Wu 1 , Xiao Tian 1 , Qian Chen 1 , Ming-Yu Wu 1 , Shun Feng 1
Chemical Communications ( IF 4.9 ) Pub Date : 2023-03-14 , DOI: 10.1039/d3cc00088e Mengzhao Wen 1 , Haizhu Shi 1 , Yu Wan 1 , Jiateng Wu 1 , Xiao Tian 1 , Qian Chen 1 , Ming-Yu Wu 1 , Shun Feng 1
Affiliation
A magnetic molecularly imprinted polymer was developed with an epitope peptide of human VEGF as a template via an epitope blotting technique. As a drug-free agent, the nanoparticles can significantly suppress the proliferation of tumor cells by integrating anti-angiogenesis and photothermotherapy. This work provides a successful example of the design of multimodal antineoplastic drugs.
中文翻译:
用于肿瘤无药物抗血管生成和光热治疗的人 VEGF 磁性分子印迹聚合物
以人VEGF表位肽为模板,通过表位印迹技术开发了一种磁性分子印迹聚合物。作为一种非药物制剂,纳米粒子通过抗血管生成和光热疗法相结合,可以显着抑制肿瘤细胞的增殖。这项工作为多模式抗肿瘤药物的设计提供了一个成功的例子。
更新日期:2023-03-14
中文翻译:
用于肿瘤无药物抗血管生成和光热治疗的人 VEGF 磁性分子印迹聚合物
以人VEGF表位肽为模板,通过表位印迹技术开发了一种磁性分子印迹聚合物。作为一种非药物制剂,纳米粒子通过抗血管生成和光热疗法相结合,可以显着抑制肿瘤细胞的增殖。这项工作为多模式抗肿瘤药物的设计提供了一个成功的例子。