A study using a multi-organoid platform and state-of-the-art transcriptional profiling identifies potential therapeutic targets against SARS-CoV-2. The authors find that CIART, a gene involved in circadian regulation, promotes SARS-CoV-2 infection by regulating the retinoid X receptor pathway and fatty acid synthesis.

中文翻译：

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将 SARS-CoV-2 与生物钟联系起来

一项使用多类器官平台和最先进的转录谱分析的研究确定了针对 SARS-CoV-2 的潜在治疗靶点。作者发现，参与昼夜节律调节的基因 CIART 通过调节类视黄醇 X 受体通路和脂肪酸合成促进 SARS-CoV-2 感染。