Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.,JAMA Neurology

当前位置： X-MOL 学术 › JAMA Neurol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.
JAMA Neurology ( IF 29.0 ) Pub Date : 2023-02-27 , DOI: 10.1001/jamaneurol.2023.0001
Adit Friedberg _{1,

2} , Lorenzo Pasquini _{1,

3} , Ryan Diggs ₁ , Erika A. Glaubitz ₁ , Lucia Lopez ₁ , Ignacio Illán-Gala _{2,

4,

5} , Leonardo Iaccarino _{1,

6} , Renaud La Joie ₁ , Nidhi Mundada ₁ , Marguerite Knudtson ₁ , Kyra Neylan ₁ , Jesse Brown ₁ , Isabel Elaine Allen _{1,

2} , Katherine P. Rankin _{1,

2} , Luke W. Bonham _{1,

7} , Jennifer S. Yokoyama _{1,

7} , Eliana M. Ramos ₈ , Daniel H. Geschwind _{9,

10,

11} , Salvatore Spina ₁ , Lea T. Grinberg _{1,

12} , Zachary A. Miller ₁ , Joel H. Kramer ₁ , Howard Rosen ₁ , Maria Luisa Gorno-Tempini ₁ , Gil Rabinovici _{1,

13} , William W. Seeley _{1,

12} , Bruce L. Miller _{1,

2}

Affiliation

Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco
Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland
Neuroscape, University of California, San Francisco
Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
Centro de Investigación en Red-Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain
now with Eli Lilly and Company, Philadelphia, Pennsylvania
Department of Radiology and Biomedical Imaging, University of California, San Francisco
Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles
Program in Neurogenetics, Center for Autism Research and Treatment Semel Institute for Neuroscience and Human Behavior, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles
Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles
Institute for Precision Health, University of California, Los Angeles
Department of Pathology, University of California, San Francisco
Associate Editor, JAMA Neurology

The neurological substrates of visual artistic creativity (VAC) are unknown. VAC is demonstrated here to occur early in frontotemporal dementia (FTD), and multimodal neuroimaging is used to generate a novel mechanistic hypothesis involving dorsomedial occipital cortex enhancement. These findings may illuminate a novel mechanism underlying human visual creativity.

中文翻译：