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Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest.
JAMA Neurology ( IF 29.0 ) Pub Date : 2023-03-06 , DOI: 10.1001/jamaneurol.2023.0050
Nicholas J Ashton, Marion Moseby-Knappe, Andrea L Benedet, Lana Grötschel, Juan Lantero-Rodriguez, Thomas K Karikari, Christian Hassager, Matt P Wise, Pascal Stammet, Jesper Kjaergaard, Hans Friberg, Niklas Nielsen, Tobias Cronberg, Henrik Zetterberg, Kaj Blennow

Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential alterations due to alternative mechanisms, such as hypoxia in patients resuscitated from cardiac arrest, are not known.

中文翻译:

院外心脏骤停患者的阿尔茨海默病血液生物标志物。

血液磷酸化 tau (p-tau) 和淀粉样蛋白-β 肽 (Aβ) 是阿尔茨海默病 (AD) 病理学的有前途的外周生物标志物。然而,由于替代机制(例如从心脏骤停复苏的患者缺氧)导致的潜在改变尚不清楚。
更新日期:2023-03-06
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