A highly efficient metal-ligand bifunctional pincer-type Ru(II) catalyst (L^OH-Ru-Cl) containing proton-responsive 2-hydroxypyridyl group has been designed and synthesized. The as-synthesized Ru(II) catalyst was definitely characterized by single-crystal X-ray diffraction. The developed Ru(II) catalyst exhibited excellent performance for the β-alkylation of secondary alcohols with primary alcohols. The optimized experiments have demonstrated that the existence of hydroxyl (-OH) group, as well as its position contained in pyridine ligand are crucial for the β-alkylation reaction. As far as we know, this is the first investigation towards the effect of position of hydroxyl (-OH) group contained in unsymmetric pincer-type catalyst on the performance of β-alkylation. The developed L^OH-Ru-Cl catalyst may provide an enlightening role for synthesis of Ru(II) catalyst contained various position of hydroxyl (-OH) groups for industrial β-alkylation reactions.

设计并合成了一种含有质子响应性 2-羟基吡啶基的高效金属配体双功能钳型 Ru(II) 催化剂 (L ^{OH -Ru-Cl)。}合成后的 Ru(II) 催化剂通过单晶 X 射线衍射明确表征。开发的 Ru(II) 催化剂在仲醇与伯醇的 β-烷基化反应中表现出优异的性能。优化后的实验表明，羟基 (-OH) 基团的存在及其在吡啶配体中的位置对于 β-烷基化反应至关重要。据我们所知，这是首次研究不对称钳形催化剂中羟基（-OH）基团的位置对β-烷基化性能的影响。发达的L ^OH-Ru-Cl催化剂可能对合成含不同位置羟基(-OH)基团的Ru(II)催化剂用于工业β-烷基化反应具有启发作用。