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+TIPs condense on microtubule plus-ends
Nature Cell Biology ( IF 21.3 ) Pub Date : 2023-01-17 , DOI: 10.1038/s41556-022-01068-7
Bernardo Gouveia 1 , Sabine Petry 2
Affiliation  

End-binding proteins attach to the dynamic plus-ends of microtubules in order to regulate microtubule polymerization and the transport of other plus-end tracking proteins (+TIPs). Three new studies dissect the multivalent interactions that constitute distinct +TIP networks and reveal that they give rise to liquid-like biomolecular condensates.

中文翻译:

+TIPs 浓缩在微管加端

末端结合蛋白附着在微管的动态加端上,以调节微管聚合和其他加端跟踪蛋白 (+TIP) 的转运。三项新研究剖析了构成不同 +TIP 网络的多价相互作用,揭示了它们会产生类似液体的生物分子凝聚物。
更新日期:2023-01-18
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