The utility of active proteases as biomarkers is often limited by overlapping substrate specificity. Here, this feature is leveraged to develop a quantitative pattern-recognition sensing system driven by the degradation patterns of peptide–peptoid hybrid substrates to classify proteases and estimate their concentration by multivariate data analysis.

中文翻译：

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用于蛋白酶定量模式识别传感的 Peptomer 底物

活性蛋白酶作为生物标志物的效用通常受到重叠底物特异性的限制。在这里，利用此功能开发由肽-拟肽杂化底物的降解模式驱动的定量模式识别传感系统，以对蛋白酶进行分类并通过多变量数据分析估计其浓度。