Intracerebral hemorrhage (ICH) is one of the most dangerous types of strokes with a high morbidity and mortality rate. Currently, the treatment of ICH is not well developed, mainly because its mechanisms are still unclear. Inflammation is one of the main types of secondary injury after ICH and catalyzes the adverse consequences of ICH. A large number of immune cells are involved in neuroinflammation, such as microglia, astrocytes, oligodendrocytes, lymphocytes, macrophages, and neutrophils. Nevertheless, the characteristics and crosstalk of immune cells have not been fully elucidated. In this review, we endeavor to delve into the respective characteristics of immune cells and their interactions in neuroimmune inflammation, and further elucidate favorable immunotherapeutic approaches regarding ICH, and finally present an outlook.

中文翻译：

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脑出血后免疫细胞的标志和串扰：免疫治疗前景

脑出血 (ICH) 是最危险的中风类型之一，具有很高的发病率和死亡率。目前，脑出血的治疗还没有很好的发展，主要是因为其机制尚不明确。炎症是脑出血后继发性损伤的主要类型之一，并催化脑出血的不良后果。大量免疫细胞参与神经炎症，如小胶质细胞、星形胶质细胞、少突胶质细胞、淋巴细胞、巨噬细胞和中性粒细胞。然而，免疫细胞的特征和串扰尚未完全阐明。在这篇综述中，我们努力深入研究免疫细胞的各自特征及其在神经免疫炎症中的相互作用，并进一步阐明有利的 ICH 免疫治疗方法，并最终提出展望。