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The DNA Phosphorothioation Restriction-Modification System Influences the Antimicrobial Resistance of Pathogenic Bacteria
Microbiology Spectrum Pub Date : 2023-01-04 , DOI: 10.1128/spectrum.03509-22
Congrui Xu 1 , Jing Rao 1 , Yuqing Xie 1 , Jiajun Lu 2 , Zhiqiang Li 1 , Changjiang Dong 1 , Lianrong Wang 1 , Jinghong Jiang 3 , Chao Chen 4 , Shi Chen 1, 4
Affiliation  

In this study, we demonstrated the effect of DNA PT modification-based R-M systems on horizontal gene transfer of AMR genes in pathogenic bacteria. We show that there is no apparent association between the genetic background of the strains harboring PT R-Ms and the number of AMR genes or the kinds of gene families.

中文翻译:

DNA硫代磷酸化限制性修饰系统影响病原菌耐药性

在这项研究中,我们证明了基于 DNA PT 修饰的 RM 系统对病原菌 AMR 基因水平基因转移的影响。我们发现,携带 PT R-M 的菌株的遗传背景与 AMR 基因的数量或基因家族的种类之间没有明显的关联。
更新日期:2023-01-04
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