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Multidimensional Assessment of Subjective Well-being and Risk of Dementia: Findings from the UK Biobank Study
Journal of Happiness Studies ( IF 4.087 ) Pub Date : 2022-12-29 , DOI: 10.1007/s10902-022-00613-3
Xianghe Zhu 1, 2 , Martina Luchetti 1 , Damaris Aschwanden 1 , Amanda A Sesker 1 , Yannick Stephan 3 , Angelina R Sutin 1 , Antonio Terracciano 1
Affiliation  

This study aimed to examine the associations between subjective well-being (SWB) and risk of all-cause dementia, Alzheimer’s disease (AD), and vascular dementia (VD). We adopted a multidimensional approach to SWB that included the level and breadth of SWB, the latter indicating the extent to which SWB spreads across life domains. Participants (= 171,197; mean age = 56.78; SD = 8.16 years) were part of the UK Biobank and were followed up to 8.78 years. Domain-general and domain-specific SWB were measured by single items, and the breadth of SWB was indexed with a cumulative score of satisfaction across domains. Dementia incidence was ascertained through hospital and death records. Cox regression was used to examine the association between SWB indicators and risk of all-cause dementia, AD, and VD. General happiness, health and family satisfaction, and satisfaction breadth (satisfaction in multiple domains) were associated with lower risk of all-cause dementia. The associations held after accounting for socio-demographics, health, behavioral, and economic covariates, and depressive symptoms. Health satisfaction and the breadth of satisfaction were also associated with lower risk of AD and VD, with a pattern of slightly stronger associations for VD compared to AD. Some life domains (e.g., health) may be more fruitfully targeted to promote well-being and help protect against dementia, but it is also important to enhance well-being across multiple domains to maximize the protective effects.



中文翻译:

主观幸福感和痴呆症风险的多维评估:英国生物银行研究的结果

本研究旨在探讨主观幸福感 (SWB) 与全因痴呆、阿尔茨海默病 (AD) 和血管性痴呆 (VD) 风险之间的关联。我们对主观幸福感采取了多维度的方法,包括主观幸福感的水平和广度,后者表明主观幸福感在生活领域的传播程度。参与者( = 171,197;平均年龄 = 56.78;SD = 8.16 岁)是英国生物银行的一部分,随访时间长达 8.78 年。一般领域和特定领域的主观幸福感是通过单个项目来衡量的,而主观幸福感的广度则以跨领域的累积满意度得分为索引。痴呆症发病率是通过医院和死亡记录确定的。Cox 回归用于检查 SWB 指标与全因痴呆、AD 和 VD 风险之间的关联。总体幸福感、健康和家庭满意度以及满意度广度(多个领域的满意度)与较低的全因痴呆风险相关。这些关联是在考虑了社会人口统计、健康、行为和经济协变量以及抑郁症状后得出的。健康满意度和满意度的广度也与较低的 AD 和 VD 风险相关,与 AD 相比,VD 的关联性稍强。某些生活领域(例如健康)可能更有效地促进福祉并帮助预防痴呆症,但增强多个领域的福祉以最大限度地发挥保护作用也很重要。

更新日期:2022-12-30
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