In this work, a new ynamide scaffold has been designed, synthesized and later applied in a gold-catalyzed cycloisomerization reaction to access pyrrole containing α,β-unsaturated ketones in low-to-moderate yields. Interestingly, the trans product has been obtained as a major isomer.

中文翻译：

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金 (I) 催化和 PTSA 促进的 Ynamides 环化异构化以获得吡咯取代的 α,β-不饱和酮**

在这项工作中，设计、合成了一种新的 ynamide 支架，随后将其应用于金催化的环化异构化反应，以低至中等收率获得含有 α,β-不饱和酮的吡咯。有趣的是，反式产物已作为主要异构体获得。