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A biocompatible iron doped graphene based cathode for an implantable glucose biofuel cell
Electrochimica Acta ( IF 6.6 ) Pub Date : 2022-11-29 , DOI: 10.1016/j.electacta.2022.141627
G. Menassol , L. Dubois , M. Nadolska , P. Vadgama , D.K. Martin , A. Zebda

In this study we propose the use of an iron/nitrogen co-doped reduced graphene oxide (Fe/N-rGO) based electrode as a cathode for a future glucose biofuel cell application. We used a mechanical compression process to fabricate cathodes in the form of pellets. We studied electrocatalytic activity toward oxygen reduction of the cathode under physiological solution conditions. Our results demonstrated the capacity of these cathodes to operate under these conditions with long-term stability exceeding two years with only 8% loss of activity. Cytotoxicity tests performed under standard in vitro cell-culture conditions showed that cathodes did not exhibit any toxic effect and thereby are promising for in vivo applications.



中文翻译:

用于植入式葡萄糖生物燃料电池的生物相容性铁掺杂石墨烯基阴极

在这项研究中,我们建议使用铁/氮共掺杂还原氧化石墨烯 (Fe/N-rGO) 基电极作为未来葡萄糖生物燃料电池应用的阴极。我们使用机械压缩工艺制造颗粒形式的阴极。我们研究了在生理溶液条件下对阴极氧还原的电催化活性。我们的结果证明了这些阴极在这些条件下运行的能力,长期稳定性超过两年,仅损失 8% 的活性。在标准体外细胞培养条件下进行的细胞毒性试验表明,阴极没有表现出任何毒性作用,因此有望用于体内应用。

更新日期:2022-12-01
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