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Passerini Reaction to Access α-Hydroxy Amides by Facile Decarbonylation/Decarboxylation of Oxalic Acid
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2022-11-29 , DOI: 10.1002/ejoc.202201199
Luan Alves Martinho 1 , Thaissa Pasquali F. Rosalba 1 , Carlos Kleber Z. Andrade 2
Affiliation  

α-Hydroxy amides were easily obtained through a novel and direct approach through decarbonylation/decarboxylation of α-acyloxy amide adducts (originated from Passerini reactions with oxalic acid) under solvent-free conditions with microwave heating.

中文翻译:

通过草酸的易脱羰基/脱羧基反应获得 α-羟基酰胺的 Passerini 反应

α-羟基酰胺很容易通过一种新颖而直接的方法获得,即在无溶剂条件下用微波加热对 α-酰氧基酰胺加合物(源自 Passerini 与草酸的反应)进行脱羰/脱羧。
更新日期:2022-11-29
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