Nanocrystals enclosed by high-index facets (HIFs) have drawn considerable attention due to their large number of low coordinate atoms, as well as their remarkable electrical properties and catalysis activity. In this article, a novel non-enzymatic electrochemical glucose sensor based on the Pt₂Pd₁ alloy nanocrystals (NCs) with HIFs was established. The mechanism of enhancing sensor performance was investigated by analyzing the composition and surface texture of Pt₂Pd₁ alloy NCs. The results showed that as-synthesized Pt₂Pd₁ alloy NCs had a larger electrochemical active surface area (ECSA). In neutral media, all the test results demonstrated the non-enzymatic glucose sensor based on Pt₂Pd₁ alloy NCs showed a good linear range of 1×10^–6 M to 4×10^–2 M with a detection limit of 0.245 μM/L (S/N = 3), good sensitivity of 31.3 μA mM^–1 cm^–2 and fast response time (t < 3 s). Furthermore, the sensor also exhibited good stability, reproducibility, and excellent anti-interference performance toward ascorbic acid (AA), uric acid (UA), and fructose (Fru). The HIFs and synergistic effects between Pt and Pd were key factors for sensor performance enhancement.

被高折射率晶面 (HIF) 包围的纳米晶体由于其大量的低配位原子以及卓越的电学性能和催化活性而备受关注。在本文中，建立了一种基于具有 HIF 的 Pt ₂ Pd ₁合金纳米晶体 (NCs) 的新型非酶促电化学葡萄糖传感器。通过分析 Pt ₂ Pd ₁合金 NCs 的成分和表面结构，研究了提高传感器性能的机制。结果表明，合成后的Pt ₂ Pd ₁合金 NCs 具有更大的电化学活性表面积 (ECSA)。在中性介质中，所有测试结果均表明基于Pt ₂ Pd ₁合金NCs的非酶葡萄糖传感器在1×10 ^–6 M至4×10 ^–2 M的良好线性范围内具有良好的线性范围，检测限为0.245  μM/ L (S/N = 3)，31.3 μA mM ^–1 cm ^–2的良好灵敏度和快速响应时间 (t < 3  s)。此外，该传感器还表现出良好的稳定性、重现性以及对抗坏血酸（AA）、尿酸（UA）和果糖（Fru）的优异抗干扰性能。Pt 和 Pd 之间的 HIF 和协同效应是提高传感器性能的关键因素。