Engineering surface chemistry to precisely control interfacial interactions is crucial for fabricating superior antifouling coatings and separation membranes. Here, we present a hydrophobic chain engineering strategy to regulate membrane surface at a molecular scale. Hydrophilic phytic acid and hydrophobic perfluorocarboxylic acids are sequentially assembled on a graphene oxide membrane to form an amphiphilic surface. The surface energy is reduced by the introduction of the perfluoroalkyl chains while the surface hydration can be tuned by changing the hydrophobic chain length, thus synergistically optimizing both fouling-resistance and fouling-release properties. It is found that the surface hydration capacity changes nonlinearly as the perfluoroalkyl chain length increases from C₄ to C₁₀, reaching the highest at C₆ as a result of the more uniform water orientation as demonstrated by molecular dynamics simulations. The as-prepared membrane exhibits superior antifouling efficacy (flux decline ratio <10%, flux recovery ratio ~100%) even at high permeance (~620 L m⁻² h⁻¹ bar⁻¹) for oil-water separation.

工程表面化学以精确控制界面相互作用对于制造优质防污涂层和分离膜至关重要。在这里，我们提出了一种疏水链工程策略，以在分子尺度上调节膜表面。亲水性植酸和疏水性全氟羧酸依次组装在氧化石墨烯膜上，形​​成两亲性表面。通过引入全氟烷基链降低了表面能，同时可以通过改变疏水链长度来调节表面水合作用，从而协同优化抗污和防污性能。结果发现，随着全氟烷基链长度从 C ₄增加到 C _{10 ，表面水合能力呈非线性变化}，由于分子动力学模拟所证明的更均匀的水取向，在 C ₆处达到最高。即使在用于油水分离的高渗透率（~620 L m ^-2 h ^-1 bar ^{-1 ）下，所制备的膜也表现出优异的防污功效（通量下降率<10%，通量恢复率~100%）。}