当前位置: X-MOL 学术Org. Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Mechanistic Insights into Tf2O-Promoted Electrophilic Activation of 2-Propynamides and a New Synthesis of 2,4-Disubstituted Quinolines
Organic Letters ( IF 5.2 ) Pub Date : 2022-11-28 , DOI: 10.1021/acs.orglett.2c03565
Lidong Shan 1 , Hongchen Li 1 , Weiping Zheng 1 , Xingyong Wang 1 , Xinyan Wang 1 , Yuefei Hu 1
Affiliation  

Direct evidence explaining why 2-propynamides have never been used as substrates in Tf2O-promoted electrophilic activations was obtained. Furthermore, a new method for the synthesis of structurally special 2,4-disubstituted quinolines was developed, by which the substituent at position 2 of quinolines can be diversified easily.

中文翻译:

Tf2O 促进 2-丙酰胺的亲电活化和 2,4-二取代喹啉的新合成的机理洞察

获得了直接证据来解释为什么 2-丙炔胺从未用作 Tf 2 O 促进的亲电激活中的底物。此外,还开发了一种合成结构特殊的2,4-二取代喹啉的新方法,该方法可以很容易地实现喹啉2位取代基的多样化。
更新日期:2022-11-28
down
wechat
bug