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Pentacyclic triterpene acids, rotungenic acid and barbinervic acid, from fresh leaves of Diospyros kaki Thunberg and their glutaminase inhibitory activities
Natural Product Research ( IF 2.2 ) Pub Date : 2022-11-26 , DOI: 10.1080/14786419.2022.2150765 Atsumi Shimada 1 , Hiroshi Ueno 2 , Kenta Yamamoto 3 , Kohei Kawabata 4 , Masanori Inagaki 4
Natural Product Research ( IF 2.2 ) Pub Date : 2022-11-26 , DOI: 10.1080/14786419.2022.2150765 Atsumi Shimada 1 , Hiroshi Ueno 2 , Kenta Yamamoto 3 , Kohei Kawabata 4 , Masanori Inagaki 4
Affiliation
Glutaminase is an important target that is often over-expressed in neurodegenerative and lifestyle-related diseases but few effective inhibitors of this enzyme have yet reached clinical trials. Thr...
中文翻译：
柿鲜叶中的五环三萜酸、圆藤酸和小叶木酸及其谷氨酰胺酶抑制活性
谷氨酰胺酶是一个重要的靶标，在神经退行性疾病和生活方式相关疾病中经常过度表达，但这种酶的有效抑制剂尚未进入临床试验。特...
更新日期：2022-11-26
中文翻译：
柿鲜叶中的五环三萜酸、圆藤酸和小叶木酸及其谷氨酰胺酶抑制活性
谷氨酰胺酶是一个重要的靶标，在神经退行性疾病和生活方式相关疾病中经常过度表达，但这种酶的有效抑制剂尚未进入临床试验。特...
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