From a CH₂Cl₂-soluble fraction of the stem barks of Taxus wallichiana, one new abeo-icetexane-type diterpenoid, taxamairin I (1), was isolated. Its absolute configuration was elucidated based on spectroscopic interpretation and time-dependent density functional theory (TD-DFT) calculation of optical rotation. In addition, the plausible biosynthesis pathway for the formation of the new abeo-icetexane-type diterpenoid was proposed. Taxamairin I (1), at a concentration of 100 μM, did not show cytotoxicity against Hep3B human liver cancer cell lines.

中文翻译：

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红豆杉茎皮中新的 abeo-Icetexane 型二萜类化合物

从红豆杉(Taxus wallichiana)茎皮的CH ₂ Cl ₂可溶部分中，分离出一种新的abeo -icetexane型二萜类化合物，taxamarin I ( 1 )。基于光谱解释和旋光时间相关密度泛函理论（TD-DFT）计算阐明了其绝对构型。此外，还提出了形成新的abeo -icetexane 型二萜类化合物的合理生物合成途径。浓度为 100 μM 的紫杉木林 I ( 1 ) 未表现出针对 Hep3B 人肝癌细胞系的细胞毒性。