Objective

This pre-registered systematic review synthesised and evaluated the existing literature on self-reported mental health and wellbeing of siblings of individuals with neurodevelopmental conditions (NDCs).

Methods

From 2437 identified studies published 2000–2022, 81 studies were included: 14 population- or cohort-based, 39 quantitative, 7 mixed method, and 21 qualitative outcome studies.

Results

Seven sibling mental health (any psychiatric disorder, anxiety, depression, bipolar disorder, schizophrenia, internalising and externalising difficulties) and five wellbeing indicators were identified (quality of life, emotional adjustment, social wellbeing, somatic/physical wellbeing, and resilience/growth). Overall, siblings had increased risk of any psychiatric disorder, but they also reported experiences of growth and resilience, primarily in qualitative studies. 41 risk factors and 24 resilience factors associated with these outcomes were identified; the most frequently cited risk factor was symptom severity of the NDC sibling, while the most common resilience factor was adaptive/active coping at the individual sibling level. Studies showed high methodological heterogeneity and 90 different self-report measures were used.

Conclusions

Sibling mental health indictors are heterogeneous and cumulative risk factors may result in poorer wellbeing. There is a need for consistent reporting of family and sibling characteristics, a strengths-based approach to assessment, and identification of protective and resilience-promoting factors.

中文翻译：

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影响神经发育疾病患者兄弟姐妹心理健康和福祉的风险和复原力因素：一项混合方法系统评价

客观的

这篇预先注册的系统评价综合并评估了有关神经发育疾病 (NDC) 患者的兄弟姐妹自我报告的心理健康和福祉的现有文献。

方法

从 2000 年至 2022 年发表的 2437 项已确定研究中，纳入了 81 项研究：14 项基于人群或队列的研究、39 项定量研究、7 项混合方法研究和 21 项定性结果研究。

结果

确定了七种同胞心理健康（任何精神障碍、焦虑、抑郁、双相情感障碍、精神分裂症、内化和外化困难）和五项幸福指标（生活质量、情绪调节、社会幸福、躯体/身体健康和复原力/成长） . 总体而言，兄弟姐妹患任何精神疾病的风险增加，但他们也报告了成长和恢复力的经历，主要是在定性研究中。确定了与这些结果相关的 41 个风险因素和 24 个弹性因素；最常被提及的风险因素是 NDC 兄弟姐妹的症状严重程度，而最常见的恢复力因素是个体兄弟姐妹层面的适应性/积极应对。研究显示了高度的方法异质性，并使用了 90 种不同的自我报告措施。

结论

兄弟姐妹的心理健康指标是异质的，累积的风险因素可能导致较差的幸福感。需要一致地报告家庭和兄弟姐妹的特征、基于优势的评估方法以及识别保护性和恢复力促进因素。