Carbamazepine (CBZ) is a frequently-detected aqueous pharmaceutical due to its extensive use and persistence in the environment. CBZ could not be efficiently removed by biological processes which led to its disposal in natural water bodies. This study coupled the Fenton process as pretreatment with the activated sludge process for aqueous CBZ removal. Fenton degradation studies showed that the application of excessive reagents might cause a decrease in CBZ removal. Apparent CBZ degradation at neutral pH supported the use of the Fenton process as pretreatment for CBZ removal. Treated with the hybrid combination system, CBZ, COD, and TOC removal were enhanced. The EEM analysis evidenced the biodegradable intermediates formed during the hybrid process. CBZ degradation pathways were explored using LC-MS analytical results and literature studies. Given the low biodegradability of CBZ, using the Fenton process as a pretreatment before sequencing batch reactor-activated sludge (SBR-AS) is an alternative to improve the aqueous CBZ treatment.

卡马西平 (CBZ) 是一种经常检测到的水性药物，因为它具有广泛的用途和在环境中的持久性。CBZ 无法通过生物过程有效去除，导致其在天然水体中处置。本研究将芬顿工艺作为预处理与活性污泥工艺相结合，以去除水性 CBZ。Fenton 降解研究表明，过量试剂的应用可能会导致 CBZ 去除率下降。在中性 pH 值下明显的 CBZ 降解支持使用 Fenton 工艺作为 CBZ 去除的预处理。采用混合组合系统处理后，CBZ、COD 和 TOC 去除率提高。EEM 分析证明了在混合过程中形成了可生物降解的中间体。使用 LC-MS 分析结果和文献研究探索了 CBZ 降解途径。