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In Situ Enzyme Immobilization by Covalent Organic Frameworks
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2022-11-04 , DOI: 10.1002/anie.202213405
Clémence Sicard 1
Affiliation  

Y. Chen and co-workers recently expanded the range of crystalline porous solids for the in situ encapsulation of enzymes to covalent organic frameworks (COFs). The designed enzyme@COF biocatalyst exhibited high enzyme loading with minimal leaching, high catalytic activity and selectivity, chemical and long-term stability, and recyclability while also allowing a scale-up to a few grams.

中文翻译:

通过共价有机骨架原位固定酶

Y. Chen 及其同事最近扩大了用于将酶原位封装到共价有机框架 (COF) 的结晶多孔固体的范围。设计的 enzyme@COF 生物催化剂表现出高酶载量和最少的浸出、高催化活性和选择性、化学和长期稳定性以及可回收性,同时还允许放大到几克。
更新日期:2022-11-04
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