Gaseous organic compounds, mainly volatile organic compounds (VOCs), have become a wide concern in various indoor environments where we spend the majority of our daily time. The sources, compositions, variations, and sinks of indoor VOCs are extremely complex, and their potential impacts on human health are less understood. Owing to the deployment of the state-of-the-art real-time mass spectrometry during the last two decades, our understanding of the sources, dynamic changes and chemical transformations of VOCs indoors has been significantly improved. This review aims to summarize the key findings from mass spectrometry measurements in recent indoor studies including residence, classroom, office, sports center, etc. The sources and sinks, compositions and distributions of indoor VOCs, and the factors (e.g., human activities, air exchange rate, temperature and humidity) driving the changes in indoor VOCs are discussed. The physical and chemical processes of gas-particle partitioning and secondary oxidation processes of VOCs, and their impacts on human health are summarized. Finally, the recommendations for future research directions on indoor VOCs measurements and indoor chemistry are proposed.

气态有机化合物，主要是挥发性有机化合物 (VOC)，已成为我们日常大部分时间所处的各种室内环境中广泛关注的问题。室内 VOC 的来源、成分、变化和汇极其复杂，其对人类健康的潜在影响知之甚少。由于在过去二十年中部署了最先进的实时质谱法，我们对室内 VOC 的来源、动态变化和化学转化的理解得到了显着改善。本综述旨在总结近期住宅、教室、办公室、体育中心等室内研究中质谱测量的主要发现。汇率，温度和湿度）驱动室内挥发性有机化合物的变化进行了讨论。总结了挥发性有机化合物的气粒分离和二次氧化过程的物理化学过程及其对人体健康的影响。最后，对室内VOCs测量和室内化学的未来研究方向提出了建议。