To date, multiple graphene@MXene hybrids have been reported via various synthesis approaches, but almost all the graphene@MXene hybrids inevitably used the reduced graphene oxide that prepared by chemical oxidation/reduction method, which generally involved the complex and dangerous operation procedure, and the highly toxic chemical reagent. How to prepare graphene@MXene hybrid through a simple, safe and eco-friendly synthetic route is highly desired. Compared with traditional synthesis technology, ultrasound synthesis strategy displays the merits of simplicity, low cost and environment protection. Herein, MXene (Ti₃C₂T_x) nanoflakes coupled with graphene nanosheets (graphene@MXene) were prepared in N-methylpyrrolidone (NMP) by simple ultrasound-assisted liquid-phase exfoliation method for the first time. Besides, the effect of types of solvent with different viscocity, sonication temperature and sonication duration time on the property of graphene@MXene hybrids were systematacially investigated. It is found the liquid-phase exfoliated graphene owned excellent electron transfer ability and the MXene (Ti₃C₂T_x) nanoflakes possessed outstanding adsorption property, the as-synthesized graphene@MXene hybrid exhibited significant signal synergistic enhancement effect toward the oxidation of hazardous veterinary drug residue compound (chlorpromazine) and food additives (rhodamine B). Based on this, a novel and sensitive electrochemical sensor was fabricated, the linear detection ranges were 5 nM to 0.5 μM for chlorpromazine with sensitivity of 1090 µA μM⁻¹ cm⁻², and 10 nM to 2.5 μM for rhodamine B with sensitivity of 440 and 102.14 µA μM⁻¹ cm⁻². Besides, the detection limits were evaluated to be as low as 1.25 nM and 2.45 nM for chlorpromazine and rhodamine B, respectively.

迄今为止，已经通过各种合成方法报道了多种石墨烯@MXene杂化物，但几乎所有的石墨烯@MXene杂化物都不可避免地使用了通过化学氧化/还原法制备的还原氧化石墨烯，其通常涉及复杂且危险的操作过程，并且剧毒化学试剂。如何通过简单、安全和环保的合成路线制备石墨烯@MXene 杂化物是人们迫切需要的。与传统的合成技术相比，超声合成策略具有简单、低成本、环保等优点。在此，MXene (Ti ₃ C ₂ T _x ) 纳米薄片与石墨烯纳米片 (graphene@MXene) 结合在N中制备-甲基吡咯烷酮 (NMP) 首次采用简单的超声辅助液相剥离法。此外，系统地研究了不同粘度、超声处理温度和超声处理持续时间的溶剂类型对石墨烯@MXene杂化物性能的影响。发现液相剥离石墨烯具有优异的电子转移能力，MXene (Ti ₃ C ₂ T _x）纳米薄片具有出色的吸附性能，合成后的石墨烯@MXene杂化物对有害兽药残留化合物（氯丙嗪）和食品添加剂（罗丹明B）的氧化表现出显着的信号协同增强作用。在此基础上，制备了一种新型灵敏的电化学传感器，氯丙嗪的线性检测范围为5 nM至0.5 μM，灵敏度为1090 µA μM ^-1 cm ^-2，罗丹明B的线性检测范围为10 nM至2.5 μM，灵敏度为440和 102.14 µA μM ^-1 cm ^-2。此外，氯丙嗪和罗丹明 B 的检测限分别评估为低至 1.25 nM 和 2.45 nM。