Atomically precise titanium-oxo clusters (TOCs) are the structure and reactivity model compounds of technically important TiO₂ materials, which could help build structure–property relationships and achieve property modulation at the molecular level. However, the traditional formation of TOCs has relied on the poorly controllable hydrolysis of titanium alkoxide in the solvent for a long time, limiting the development of TOC structural chemistry to a great extent. In addition, easily hydrolyzable alkoxy groups would be still coordinated on the surface of the TOCs generated by this method, making the clusters sensitive and unstable to the moisture. To achieve controllable preparation of TOCs, we believe it is crucial to attenuate the hydrolysis of titanium ions in the formation process of a cluster. To this end, we have recently applied an effective coordination-delayed-hydrolysis (CDH) strategy for TOC synthesis, which provides powerful tools for tuning their structures.

中文翻译：

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钛-氧簇的合成和结构调节的配位-延迟水解法

原子级精确的钛氧簇 (TOC) 是技术上重要的 TiO _{2的结构和反应性模型化合物}材料，这可以帮助建立结构-性质关系并在分子水平上实现性质调节。然而，传统的 TOCs 的形成长期以来依赖于钛醇盐在溶剂中水解的不可控性，在很大程度上限制了 TOC 结构化学的发展。此外，该方法生成的TOCs表面仍会配位易水解的烷氧基，使团簇对水分敏感且不稳定。为了实现 TOC 的可控制备，我们认为在簇的形成过程中减弱钛离子的水解是至关重要的。为此，我们最近为 TOC 合成应用了一种有效的协调延迟水解 (CDH) 策略，为调整其结构提供了强大的工具。