Directed Conformational Switching of a Zinc Finger Analogue Regulates the Mechanosensing and Differentiation of Stem Cells,Angewandte Chemie International Edition

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Directed Conformational Switching of a Zinc Finger Analogue Regulates the Mechanosensing and Differentiation of Stem Cells
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2022-10-04 , DOI: 10.1002/anie.202203847
Pengchao Zhao _{1,

2,

3} , Ziqi Wang ₄ , Xian Xie ₃ , Tianshen Jiang _{1,

2} , Nathanael Chun-Him Lai ₃ , Boguang Yang ₃ , Bo Yi _{1,

2} , Hao Fu _{1,

2} , Kunyu Zhang _{1,

2} , Gang Li ₅ , Yi Wang ₄ , Liming Bian _{1,

2}

Affiliation

Conformational switching of rationally designed secondary-structure mimics of extracellular matrix proteins can be controlled via the formation a polymer–cation complex enabling the control of bio-ligand presentation for the study of cellular development.

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