Several forms of secondary hypertension carry a high risk of cardiac morbidity and mortality. Evaluation of cardiac phenotypes in secondary hypertension provides a unique opportunity to study underlying hormonal and biochemical mechanisms affecting the heart. We review the characteristics of cardiac dysfunction in different forms of secondary hypertension and clarify the mechanisms behind the higher prevalence of heart damage in these patients than in those with primary hypertension. Attention to the specific clinical/biochemical phenotypes of these conditions may assist clinicians to screen for and confirm secondary forms of hypertension. Thereby, early signs of heart damage can be recognized and monitored, allowing individualized treatment to delay or prevent evolution toward more advanced disease.

几种形式的继发性高血压具有心脏病发病率和死亡率的高风险。评估继发性高血压的心脏表型为研究影响心脏的潜在激素和生化机制提供了独特的机会。我们回顾了不同形式继发性高血压的心功能不全的特征，并阐明了这些患者心脏损伤发生率高于原发性高血压的机制。注意这些病症的特定临床/生化表型可能有助于临床医生筛查和确认继发性高血压。因此，可以识别和监测心脏损伤的早期迹象，从而允许个体化治疗延迟或防止向更晚期疾病发展。