Strategies aimed at defining, discovering, and developing alternatives to traditional antibiotics will underlie the development of sustainable agricultural systems. Among such strategies, antimicrobial peptides (AMPs) with broad-spectrum antimicrobial activity and multifaceted mechanisms of action are recognized as ideal alternatives in the post-antibiotic era. In particular, AMPs derived from microbes with active metabolisms that can adapt to a variety of extreme environments have long been sought after. Consequently, this review summarizes information on naturally occurring AMPs, including their biological activity, antimicrobial mechanisms, and the preparation of microbial-derived AMPs; it also outlines their applications and the challenges presented by their use in the agroindustry. By dissecting the research results on microbial-derived AMPs of previous generations, this study contributes valuable knowledge on the exploration and realization of the applications of AMPs in sustainable agriculture.

中文翻译：

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用于可持续农业的微生物源抗菌肽的生物勘探

旨在定义、发现和开发传统抗生素替代品的战略将成为可持续农业系统发展的基础。在这些策略中，具有广谱抗菌活性和多方面作用机制的抗菌肽（AMP）被认为是后抗生素时代的理想替代品。尤其是源自代谢活跃、能适应各种极端环境的微生物的AMP长期以来一直受到追捧。因此，本综述总结了有关天然存在的 AMP 的信息，包括其生物活性、抗菌机制以及微生物源 AMP 的制备；它还概述了它们的应用以及它们在农产工业中的使用所带来的挑战。本研究通过剖析前几代微生物源AMPs的研究成果，为探索和实现AMPs在可持续农业中的应用提供了宝贵的知识。