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A nomenclature consensus for nervous system organoids and assembloids
Nature ( IF 64.8 ) Pub Date : 2022-09-28 , DOI: 10.1038/s41586-022-05219-6
Sergiu P Pașca 1, 2 , Paola Arlotta 3, 4 , Helen S Bateup 5, 6, 7 , J Gray Camp 8, 9 , Silvia Cappello 10 , Fred H Gage 11 , Jürgen A Knoblich 12, 13 , Arnold R Kriegstein 14, 15 , Madeline A Lancaster 16 , Guo-Li Ming 17, 18, 19, 20, 21 , Alysson R Muotri 22, 23 , In-Hyun Park 24 , Orly Reiner 25 , Hongjun Song 17, 18, 19, 20, 26 , Lorenz Studer 27 , Sally Temple 28 , Giuseppe Testa 29, 30 , Barbara Treutlein 31 , Flora M Vaccarino 32, 33, 34
Affiliation  

Self-organizing three-dimensional cellular models derived from human pluripotent stem cells or primary tissue have great potential to provide insights into how the human nervous system develops, what makes it unique and how disorders of the nervous system arise, progress and could be treated. Here, to facilitate progress and improve communication with the scientific community and the public, we clarify and provide a basic framework for the nomenclature of human multicellular models of nervous system development and disease, including organoids, assembloids and transplants.



中文翻译:

神经系统类器官和组合体的命名共识

来自人类多能干细胞或原代组织的自组织三维细胞模型具有巨大的潜力,可以深入了解人类神经系统如何发育、其独特之处以及神经系统疾病如何产生、进展和治疗。在这里,为了促进进展并改善与科学界和公众的沟通,我们澄清并提供了神经系统发育和疾病的人类多细胞模型的命名法(包括类器官、组合体和移植物)的基本框架。

更新日期:2022-09-29
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