Background. Hepatocellular carcinoma is one of the malignant tumors with the highest incidence in the world. According to the latest statistics of the National Cancer Center, the incidence of liver cancer ranks fifth in malignant tumors and its mortality rate ranks second in China, which seriously threatens people’ s life and health. Aim. To investigate the value of CT perfusion parameters and apparent diffusion coefficient (ADC) of magnetic resonance imaging (MRI) diffusion weighted imaging (DWI) in the diagnosis of hepatocellular carcinoma. Methods. 43 patients with hepatocellular carcinoma and 40 patients with hepatic hemangioma treated in our hospital from August 2018 to August 2021 were selected for CT perfusion imaging and MRI examination. Results. The liver blood flow (BF), liver blood volume (BV), and hepatic artery perfusion (HAP) in the hepatocellular carcinoma group were (267.38 ± 35.59) ml/(min·100 g), (30.20 ± 8.82) ml/100 g, and (0.64 ± 0.10) ml/(min·ml), respectively, which were significantly higher than those in the hepatic hemangioma group (). The ADC value of hepatocellular carcinoma DWI sequence was (1.20 ± 0.17) ×10^-3 mm², which was significantly lower than that of hepatic hemangioma (). The area under ROC curve of BF, BV, HAP, and ADC values for hepatocellular carcinoma was 0.860, 0.754, 0.804, and 0.890, respectively. The area under ROC curve of the four groups was compared (). Conclusion. CT perfusion parameters BF, BV, HAP, and DWI sequence ADC values have certain application value in the diagnosis of hepatocellular carcinoma, and there is no significant difference between the diagnostic value of each parameter.

中文翻译：

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磁共振弥散加权成像CT灌注参数及表观弥散系数值对肝细胞癌诊断的价值

背景。肝细胞癌是世界上发病率最高的恶性肿瘤之一。据国家癌症中心最新统计，肝癌的发病率居恶性肿瘤的第五位，死亡率居全国第二位，严重威胁着人们的生命健康。瞄准。探讨CT灌注参数和磁共振成像（MRI）扩散加权成像（DWI）表观扩散系数（ADC）在肝细胞癌诊断中的价值。方法。选取2018年8月至2021年8月在我院收治的43例肝细胞癌患者和40例肝血管瘤患者进行CT灌注成像和MRI检查。结果. 肝癌组肝血流量（BF）、肝血容量（BV）、肝动脉灌注（HAP）分别为（267.38±35.59）ml/（min·100g）、（30.20±8.82）ml/100 g、（0.64±0.10）ml/（min·ml），均显着高于肝血管瘤组（）。肝细胞癌DWI序列ADC值为（1.20±0.17）×10 ^-3  mm ²，明显低于肝血管瘤（）。肝细胞癌BF、BV、HAP和ADC值的ROC曲线下面积分别为0.860、0.754、0.804和0.890。比较四组ROC曲线下面积（）。 结论。CT灌注参数BF、BV、HAP、DWI序列ADC值在肝细胞癌诊断中具有一定的应用价值，各参数的诊断价值无显着差异。