For a long time, the detection of nitroimidazole antibiotics (NIABs) has been a research focus in environmental analytical chemistry. In this work, a novel technique for the analysis of nitroimidazoles was established based on capillary electrophoresis (CE). UiO-66, synthesized using a solvothermal method, was utilized as an adsorbent in the dispersive solid-phase extraction (DSPE) of five different NIABs. The separation and detection of NIABs in environmental water samples were accomplished using the CE diode array detection method. The optimal extraction conditions were obtained after systematically studying the effects of adsorption time, the amount of extractant, and elution solvent on extraction efficiency. According to the results of the study, the limit of detections of the five NIABs were between 16 and 97 ng/mL, the relative standard deviations were between 0.32% and 0.55%, and the spike recoveries were between 87.43% and 104.8%. This study presents a novel technique for measuring NIABs in complex water samples.

中文翻译：

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分散固相萃取毛细管电泳法测定硝基咪唑类抗生素

长期以来，硝基咪唑类抗生素（NIABs）的检测一直是环境分析化学的研究热点。在这项工作中，建立了一种基于毛细管电泳 (CE) 的硝基咪唑分析新技术。使用溶剂热法合成的 UiO-66 在五种不同 NIAB 的分散固相萃取 (DSPE) 中用作吸附剂。使用 CE 二极管阵列检测方法完成了环境水样中 NIAB 的分离和检测。系统研究了吸附时间、萃取剂用量、洗脱溶剂对萃取效率的影响，得出了最佳萃取条件。根据研究结果，五种 NIAB 的检测限在 16 至 97 ng/mL 之间，相对标准偏差在0.32%和0.55%之间，加标回收率在87.43%和104.8%之间。本研究提出了一种测量复杂水样中 NIAB 的新技术。